Atf2 myeloid

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WebOct 15, 2009 · JNK1/c-Jun and p38 alpha MAPK/ATF-2 pathways are responsible for upregulation of Fas/FasL in human chronic myeloid leukemia K562 cells upon exposure to Taiwan cobra phospholipase A2 J Cell Biochem . 2009 Oct 15;108(3):612-20. doi: 10.1002/jcb.22293. WebATF2 with a tissue-specific coactivator activating signal cointegator-2 (ASC-2) potentiates the differentiation pro-cedure. ... lineages, erythroid, myeloid, or lymphoid cells (1). The vitamin A metabolite, all-trans retinoic acid, induces the granulocytic differentiation of the promyelocytic cell line U937, similar to HL60.

ATF2 Cancer Genetics Web

WebApr 14, 2024 · Progress in acute myeloid leukaemia treatment is occurring at an unprecedented pace. The past decade has witnessed an increasingly improved scientific … WebAtf2(Δ8,9)-driven tumors show enhanced pigmentation, immune infiltration, and metastatic propensity. Similar to mouse Atf2(Δ8,9), we have identified a transcriptionally inactive human ATF2 splice variant 5 (ATF2(SV5)) that enhances the growth and migration capacity of cultured melanoma cells and immortalized melanocytes. the law of business structures 2012

Atf2 Mouse Gene Details activating transcription factor 2 ...

WebMay 9, 2012 · Prostaglandin I(2) (PGI(2)) analog is regarded as a potential candidate for treating asthma. Human myeloid dendritic cells (mDCs) play a critical role in the pathogenesis of asthma. ... (2+) pathway. Iloprost suppressed TNF-α expression via the MAPK-p38-ATF2 pathway and epigenetic regulation by downregulation of histone H3K4 … WebIn this study, we show two novel points that ATF2 is re-quired for the induction of granulocytic differentiation and associates with granulocyte-specific transcription factor … WebApr 4, 2024 · National Center for Biotechnology Information th-ytncom

ATF2, a paradigm of the multifaceted regulation of transcription ...

AP-1: a double-edged sword in tumorigenesis - Nature

WebDec 19, 2013 · ATF2 regulates cell cycle-related protein expression. JNK has an important role in modulating cell cycle progression. ATF2, a transcription factor, has also been … WebDec 19, 2013 · ATF2 regulated cell cycle-related protein expression and inhibited apoptosis in selenite-treated NB4 cells. (a) ATF2 bound to the promoters of cyclin D3, cyclin A and CDK4. A ChIP assay was ... the law of canadian municipal corporationsWebJan 27, 2024 · Summary. Basic leucine zipper ATF-like transcription factor 2 (BATF2), an interferon-activated immune response regulator, is a key factor responsible for myeloid … thy tk 1827

"WebATF2 is part of cluster 44 Non-specific - Transcription with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated clustering, and therefore reflects how strongly associated it is to the cluster. " - Atf2 myeloid

Atf2 myeloid

Stroke induces disease-specific myeloid cells in the brain ... - Nature

WebSep 21, 2024 · Acute myelogenous leukemia (AML) is a cancer of the blood and bone marrow — the spongy tissue inside bones where blood cells are made. The word "acute" in acute myelogenous leukemia denotes the disease's rapid progression. It's called myelogenous (my-uh-LOHJ-uh-nus) leukemia because it affects a group of white blood … WebDec 22, 2024 · ATF4 deletion caused expansion of phenotypical HSCs with functional attrition, characterized by defective repopulating and self-renewal capacities and …

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WebFull gene name according to HGNC. Activating transcription factor 2. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. … WebAcute myeloid leukemia. ATF2. Activating transcription factor 2. AT-MSC. Adipose tissue-derived mesenchymal stem/stromal cell. BAD. Bcl-2-associated death promoter. …

WebATF2 is part of cluster 44 Non-specific - Transcription with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated clustering, and therefore … WebOct 15, 2009 · Request PDF JNK1/c-Jun and p38α MAPK/ATF-2 pathways are responsible for upregulation of Fas/FasL in human chronic myeloid leukemia K562 cells upon exposure to Taiwan cobra phospholipase A 2 ...

WebMay 1, 2024 · 1. Activating transcription factor 2 (ATF2) Activating transcription factor 2 (ATF2)—also known as cyclic AMP (cAMP) response element (CRE) binding protein 2 (CREB2) and CRE-BP1—is a member of the activating protein-1 (AP1) transcription factor family that regulates gene expression through homo-dimerization or hetero-dimerization … WebWe further demonstrated that LPS stimulated ATF2 and p300 phosphorylation and complex formation via a c-Src/NADPH oxidase/ROS/p38 MAPK pathway. Up-regulation of VCAM-1 led to enhancing monocyte adhesion to HRMCs challenged with LPS, which was inhibited by siRNAs of c-Src, p47phox, p38 MAPK, ATF2, and p300 or pretreatment with an anti …

WebJun 3, 2024 · ATF2 can contribute to regulating the expression of matrix metalloproteases (MMPs), which are zinc-dependent neutral endopeptidases that play an essential role in the process of tissue remodelling by degrading extracellular matrix (ECM) components. 41, 42 A recent study confirmed that ERK1 mediates IL-1β activation of the ERK1/ATF2 signalling ...

WebCharacterization of ATF2 dysfunction in the context of pathological conditions, particularly in cancer biology and response to therapy, will be important in understanding how pathways controlled by ATF2 or other transcription factors might be therapeutically exploited. In this review, we provide an overview of the currently known upstream ... the law of business structures pdfWebApr 4, 2024 · basic leucine zipper transcriptional factor ATF-like 2, B-ATF-2, basic leucine zipper transcription factor, ATF-like 2, suppressor of AP-1 regulated by IFN. ... Gain- and loss-of-function studies uncovered a role for Batf2 in myeloid differentiation in both murine and human systems. We thus demonstrate that chronic infection can deplete HSPCs ... the law of captureWebMar 21, 2024 · BATF2 (Basic Leucine Zipper ATF-Like Transcription Factor 2) is a Protein Coding gene. Diseases associated with BATF2 include Hepatocellular Carcinoma . Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and sequence-specific DNA binding . An important paralog of this gene is … the law of business organizationsWebJun 23, 2024 · Correlation analysis results showed that T cell CD8+ was positively correlated with myeloid dendritic cell but was negatively correlated with cancer … the law of blockchainWebNov 13, 2024 · JNK binds to ATF2 using a linear D-motif and a Zn-finger. The transactivating region of both c-Jun and ATF2 contains a MAPK binding D-motif. The structure of the JNK1-ATF2 D-motif peptide complex ... thy til stauderWebOct 15, 2009 · JNK1/c-Jun and p38 alpha MAPK/ATF-2 pathways are responsible for upregulation of Fas/FasL in human chronic myeloid leukemia K562 cells upon exposure … the law of buy-inWebOct 1, 2012 · ATF2 was found to upregulate Fas/FasL in a human chronic myeloid leukemia cell line (Chen et al., 2009). NFE2L2 (NRF2) is a transcription activator of the bZIP … thyto carrelage