WebCTCFL, a testis-specific DNA binding protein containing 11 C2H2-type zinc fingers, belongs to the CTCF zinc-finger protein family. CTCFL is responsible for insulator function, … WebChIPAb+ CTCF - ChIP Validated Antibody and Primer Set clone 1.2.1.5.4, from mouse; Synonyms: 11 zinc finger transcriptional repressor, 11-zinc finger protein, CCCTC-binding factor, CCCTC-binding factor (zinc finger protein), CTCFL paralog, transcriptional repressor CTCF; find Sigma-Aldrich-1710044 MSDS, related peer-reviewed papers, technical …
CTCF and CTCFL in cancer - ScienceDirect
WebNov 15, 2013 · Estrogens play a key role in breast cancer, with 60-70% of the cases expressing estrogen receptors (ERs), which are encoded by the ESR1 gene. CTCFL, a paralogue of the chromatin organizer CTCF, is a potential biomarker of breast cancer, but its expression in this disease is currently controversial. A positive correlation has been … WebAntibodies that detect CTCF can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation and ChIP. These antibodies target CTCF in Human, Mouse, Rat, Non-human primate and Equine samples. Our CTCF polyclonal, recombinant monoclonal and monoclonal antibodies are … ear piercing advice men
Early vertebrate origin of CTCFL, a CTCF paralog, revealed …
WebJan 28, 2024 · BORIS (CTCFL), a germline-specific paralog of CTCF, was unable to anchor cohesin to CTCF DNA binding sites. Furthermore, CTCF-BORIS chimeric constructs provided evidence that, besides the N terminus of CTCF, the first two CTCF zinc fingers, and likely the 3D geometry of CTCF-DNA complexes, are also involved in cohesin … WebCTCFL is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes. CTCFL is normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. WebNov 15, 2013 · CTCFL is a paralogue of CTCF, the gene encoding CTCF, a ubiquitous 11-zinc finger protein with highly versatile functions, such as the global three-dimensional genome organization, including intra- and interchromosomal loop formation (4–8). CTCF is involved in transcriptional silencing or activation and may function as an insulator and ... ear piercing always bleeding