NettetMouse CRISPR Knockout Pooled Library (Brie) • Uses optimized metrics that combine improved on-target activity predictions with an off-target score Doench et al. Human CRISPR Activation Pooled Library (Calabrese p65 … NettetJournal: Molecular cell Article Title: The Dystonia Gene THAP1 Controls DNA Double Strand Break Repair Choice doi: 10.1016/j.molcel.2024.03.034 Figure Lengend Snippet: KEY RESOURCES TABLE Article Snippet: CRISPR–Cas9 screen was performed using genome-scale mouse Brie CRISPR knockout pooled library (Addgene #73633) ( …
Positive selection of somatically mutated clones identifies adaptive ...
Nettet23. mar. 2016 · In 2013, a major breakthrough was achieved in gene editing and mouse knockout models. Scientists discovered how to harness the CRISPR-associated … Nettet19. mar. 2024 · High-throughput CRISPR-Cas9 screens using pooled sgRNA libraries provide an unbiased and precisely targeted method for the systematic assessment of gene function. In addition to catalog core … data mining and workflow design in healthcare
A multi-omics integrative analysis based on CRISPR screens re …
Nettet2. apr. 2024 · N/A CRiNCL - Human CRISPRi Non-coding Libraries 86538 86550 Inhibition Human Weissman 3rd 10 Varies CRISPR/Cas9-assisted Removal of Mitochondrial DNA (CARM) Library 82480 Knockout Mouse Xie N/A N/A 395 CRISPRa Discontinued Activation Human Weissman 3rd 10 198,810 CRISPRa-v2 … NettetMouse Kinome Small Guide Rna (Sgrna) Library [No, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS ... Grna Brie Library, supplied by Addgene inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, ... Nettet21. jan. 2024 · The genome-scale CRISPR knockout (GeCKO) pooled library was firstly reported by Sanjana et al. , and several libraries were subsequently developed (11–13). These genome-wide screening techniques have been applied to several cancer cell lines to clarify the mechanism driving malignancy ( 14 , 15 ). data mining and warehousing question bank