WebJun 5, 2024 · Phosphomimetic Version of the Chk1-Mediated p50 Phosphosite Ser242 Destabilises DNA Binding To evaluate the effect of modification of S248 and S337 on DNA binding, we employed the titration method and native MS to determine the dissociation constants ( K D ) for DNA binding for each of the p50 protein variants (Fig. 4 ; Table 1 ). WebWiktionary (0.00 / 0 votes) Rate this definition: phosphomimetic noun. Any agent that mimics the biological activity of phosphate.
phosphomimetetic和phosphomimetic用法上有什么区别呢? - 外语学习 - 读写翻译 …
WebNov 5, 2007 · 小木虫论坛-学术科研互动平台 » 科研生活区 » 外语学习 » 读写翻译 » phosphomimetetic和phosphomimetic用法上有什么区别呢? 2 1/1 Webde-+ phosphomimetic. Noun . dephosphomimetic (plural dephosphomimetics) (biochemistry) Any agent that mimics biological dephosphorylation can hiv prevent pregnancy
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WebMay 15, 2004 · Microinjection of antibodies against phosphorylated S353 results in a mitotic delay whilst overexpression of a S353 phosphomimetic mutant enhances the mitotic inducing effect of CDC25B. Our results demonstrate that Aurora-A phosphorylates CDC25B in vivo at the centrosome during mitosis. This phosphorylation might locally participate in … WebDec 22, 1998 · The characteristics of the IRP1 mutants containing phosphomimetic substitutions for S138 suggest that the [4Fe–4S] cluster of these proteins is more sensitive to oxygen and other cluster perturbants, than is the wt protein. To investigate this, purified IRP1 mutants were reconstituted anaerobically and exposed to air-saturated buffer as a ... WebJian you are correct that the charge is the reason why that substitution is made. Serine is often mutated to glutamic acid (sometimes aspartic acid) to mimic phosphorylation of the serine residue. can hiv positive get life insurance