WebThioredoxin Interacting Protein. Thioredoxin-interacting protein (TXNIP), also known as thioredoxin-binding protein 2 (TBP-2)/vitamin D3up-regulated protein 1 (VDUP1), is an α … WebThioredoxin (Trx) is a thermostable, 12-kDa intracellular E. coli protein that is easily overexpressed and soluble even when overexpressed up to 40% of the total cellular protein (LaVallie et al., 1993), and is very useful as a tag in avoiding inclusion body formation in recombinant protein production (LaVallie et al., 2000).
Pfam is now hosted by InterPro
Thioredoxin is a class of small redox proteins known to be present in all organisms. It plays a role in many important biological processes, including redox signaling. In humans, thioredoxins are encoded by TXN and TXN2 genes. Loss-of-function mutation of either of the two human thioredoxin genes is lethal at … See more They are found in nearly all known organisms and are essential for life in mammals. See more Thioredoxin is a 12-kD oxidoreductase protein. Thioredoxin proteins also have a characteristic tertiary structure termed the thioredoxin fold. The active site contains a dithiols in a CXXC See more Trx1 has been shown to downregulate cardiac hypertrophy, the thickening of the walls of the lower heart chambers, by interactions with … See more • RuBisCO - enzyme activity regulated by thioredoxin • Peroxiredoxin - enzyme activity regulated by thioredoxin • Thioredoxin fold • Thioredoxin reductase See more The primary function of Thioredoxin (Trx) is the reduction of oxidized cysteine residues and the cleavage of disulfide bonds. Multiple in vitro substrates for thioredoxin have … See more Thioredoxin has been shown to interact with: • ASK1, • Collagen, type I, alpha 1, See more Thioredoxin is used in skin care products as an antioxidant in conjunction with glutaredoxin and glutathione. See more WebThioredoxin (Trx) is a redox protein of approximately 12 kDa. Its primary domain is conserved across a number of Trx family members and contains a conserved catalytic site Cys-Gly-Pro-Cys. It is ubiquitous and found in many organisms from bacteria to mammals. Trx has been shown to function in cell proliferation, redox signaling and inhibition ... pork ribs slow cooker recipe easy
Transporter Protein - an overview ScienceDirect Topics
WebMay 6, 2024 · Protein disulfide isomerase (PDI) belongs to the thioredoxin superfamily, and more than 20 PDI family proteins have been identified in mammalian cells (23, 64). Most PDIs are soluble proteins located in the luminal compartment of the endoplasmic reticulum (ER), whereas some are integral membrane proteins classified as members of the … WebGlutaredoxins have been much less studied than thioredoxin, and most work has been performed on glutaredoxins from non-photosynthetic organisms, especially E. coli, yeast, ... Grxs belong to the Trx fold protein family. In fact, Grxs are the most basic representation of this fold, consisting of a central four- or five-stranded β-sheet ... WebUniProtKB reviewed (Swiss-Prot) Organism. Arabidopsis thaliana (Mouse-ear cress) Amino acids. 186. Protein existence. Evidence at protein level. Annotation score. 5/5. pork rind chips